diff --git a/rf2aa/config/inference/protein_sm.yaml b/rf2aa/config/inference/protein_sm.yaml
new file mode 100644
index 0000000..939e13e
--- /dev/null
+++ b/rf2aa/config/inference/protein_sm.yaml
@@ -0,0 +1,13 @@
+defaults:
+  - base
+
+job_name: 7qxr
+
+protein_inputs:
+  A: 
+    fasta_file: examples/protein/7qxr.fasta
+
+sm_inputs:
+  B:
+    input: examples/small_molecule/NSW_ideal.sdf
+    input_type: "sdf"
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