1. Multi-level [vmselect setup](https://docs.victoriametrics.com/cluster-victoriametrics/#multi-level-cluster-setup) in cluster setup, top-level vmselect(s) reads data from cluster-level vmselects
* Merges data from both sources. You need to turn on [deduplication](https://docs.victoriametrics.com/cluster-victoriametrics/#deduplication) to remove duplicates
1. Regional endpoints - use one regional endpoint as default and switch to another if there is an issue.
1. Load balancer - that sends queries to a particular region. The benefit and disadvantage of this setup is that it's simple.
1. Promxy - proxy that reads data from multiple Prometheus-like sources. It allows reading data more intelligently to cover the region's unavailability out of the box. It doesn't support MetricsQL yet (please check this issue).
1. Global vmselect in cluster setup - you can set up an additional subset of vmselects that knows about all storages in all regions.
* The [deduplication](https://docs.victoriametrics.com/cluster-victoriametrics/#deduplication) in 1ms on the vmselect side must be turned on. This setup allows you to query data using MetricsQL.
* The downside is that vmselect waits for a response from all storages in all regions.
### High Availability
The data is duplicated twice, and every region contains a full copy of the data. That means one region can be offline.
You don't need to set up a replication factor using the VictoriaMetrics cluster.
### Alerting
You can set up vmalert in each Ground control region that evaluates recording and alerting rules. As every region contains a full copy of the data, you don't need to synchronize recording rules from one region to another.
For alert deduplication, please use [cluster mode in Alertmanager](https://prometheus.io/docs/alerting/latest/alertmanager/#high-availability).
An additional VictoriaMetrics single can be set up in every region, scraping metrics from the main TSDB.
You also may evaluate the option to send these metrics to the neighbour region to achieve HA.
Additional context
* VictoriaMetrics Single - [https://docs.victoriametrics.com/Single-server-VictoriaMetrics.html#monitoring](https://docs.victoriametrics.com/Single-server-VictoriaMetrics.html#monitoring)