diff --git a/lib/promscrape/scraper.go b/lib/promscrape/scraper.go
index 3c2651369..c0b68edc2 100644
--- a/lib/promscrape/scraper.go
+++ b/lib/promscrape/scraper.go
@@ -231,11 +231,17 @@ func (scfg *scrapeConfig) run() {
 	cfg := <-scfg.cfgCh
 	var swsPrev []*ScrapeWork
 	updateScrapeWork := func(cfg *Config) {
-		startTime := time.Now()
-		sws := scfg.getScrapeWork(cfg, swsPrev)
-		sg.update(sws)
-		swsPrev = sws
-		scfg.discoveryDuration.UpdateDuration(startTime)
+		for {
+			startTime := time.Now()
+			sws := scfg.getScrapeWork(cfg, swsPrev)
+			retry := sg.update(sws)
+			swsPrev = sws
+			scfg.discoveryDuration.UpdateDuration(startTime)
+			if !retry {
+				return
+			}
+			time.Sleep(2 * time.Second)
+		}
 	}
 	updateScrapeWork(cfg)
 	atomic.AddInt32(&PendingScrapeConfigs, -1)
@@ -295,7 +301,7 @@ func (sg *scraperGroup) stop() {
 	sg.wg.Wait()
 }
 
-func (sg *scraperGroup) update(sws []*ScrapeWork) {
+func (sg *scraperGroup) update(sws []*ScrapeWork) (retry bool) {
 	sg.mLock.Lock()
 	defer sg.mLock.Unlock()
 
@@ -352,6 +358,7 @@ func (sg *scraperGroup) update(sws []*ScrapeWork) {
 		sg.changesCount.Add(additionsCount + deletionsCount)
 		logger.Infof("%s: added targets: %d, removed targets: %d; total targets: %d", sg.name, additionsCount, deletionsCount, len(sg.m))
 	}
+	return deletionsCount > 0 && len(sg.m) == 0
 }
 
 type scraper struct {