diff --git a/app/vmagent/remotewrite/relabel.go b/app/vmagent/remotewrite/relabel.go
index b6fe3d097..42a28e5f7 100644
--- a/app/vmagent/remotewrite/relabel.go
+++ b/app/vmagent/remotewrite/relabel.go
@@ -50,12 +50,11 @@ func resetRelabel() {
 	prcs = nil
 }
 
-func (rctx *relabelCtx) applyRelabeling(wr *prompbmarshal.WriteRequest) {
+func (rctx *relabelCtx) applyRelabeling(tss []prompbmarshal.TimeSeries) []prompbmarshal.TimeSeries {
 	if len(extraLabels) == 0 && len(prcs) == 0 {
 		// Nothing to change.
-		return
+		return tss
 	}
-	tss := wr.Timeseries
 	tssDst := tss[:0]
 	labels := rctx.labels[:0]
 	for i := range tss {
@@ -83,7 +82,7 @@ func (rctx *relabelCtx) applyRelabeling(wr *prompbmarshal.WriteRequest) {
 		})
 	}
 	rctx.labels = labels
-	wr.Timeseries = tssDst
+	return tssDst
 }
 
 type relabelCtx struct {
diff --git a/app/vmagent/remotewrite/remotewrite.go b/app/vmagent/remotewrite/remotewrite.go
index 8bb927c71..9f0dedc1a 100644
--- a/app/vmagent/remotewrite/remotewrite.go
+++ b/app/vmagent/remotewrite/remotewrite.go
@@ -105,11 +105,18 @@ func Stop() {
 // Each timeseries in wr.Timeseries must contain one sample.
 func Push(wr *prompbmarshal.WriteRequest) {
 	rctx := relabelCtxPool.Get().(*relabelCtx)
-	rctx.applyRelabeling(wr)
-
-	idx := atomic.AddUint64(&pssNextIdx, 1) % uint64(len(pss))
-	pss[idx].Push(wr.Timeseries)
-
+	tss := wr.Timeseries
+	for len(tss) > 0 {
+		// Process big tss in smaller blocks in order to reduce maxmimum memory usage
+		tssBlock := tss
+		if len(tssBlock) > maxRowsPerBlock {
+			tssBlock = tss[:maxRowsPerBlock]
+			tss = tss[maxRowsPerBlock:]
+		}
+		tssBlock = rctx.applyRelabeling(tssBlock)
+		idx := atomic.AddUint64(&pssNextIdx, 1) % uint64(len(pss))
+		pss[idx].Push(tssBlock)
+	}
 	rctx.reset()
 	relabelCtxPool.Put(rctx)
 }