diff --git a/app/vmalert/README.md b/app/vmalert/README.md
index 191105df5c..b8fd1f6508 100644
--- a/app/vmalert/README.md
+++ b/app/vmalert/README.md
@@ -525,6 +525,8 @@ The shortlist of configuration flags is the following:
      Optional bearer auth token to use for -datasource.url.
   -datasource.bearerTokenFile string
      Optional path to bearer token file to use for -datasource.url.
+  -datasource.disableKeepAlive
+     Whether to disable long-lived connections to the datasource. If true, disables HTTP keep-alives and will only use the connection to the server for a single HTTP request.
   -datasource.lookback duration
      Lookback defines how far into the past to look when evaluating queries. For example, if the datasource.lookback=5m then param "time" with value now()-5m will be added to every query.
   -datasource.maxIdleConnections int
diff --git a/app/vmalert/datasource/init.go b/app/vmalert/datasource/init.go
index 004a9b36d0..891e7f991e 100644
--- a/app/vmalert/datasource/init.go
+++ b/app/vmalert/datasource/init.go
@@ -41,7 +41,9 @@ var (
 	queryTimeAlignment = flag.Bool("datasource.queryTimeAlignment", true, `Whether to align "time" parameter with evaluation interval.`+
 		"Alignment supposed to produce deterministic results despite of number of vmalert replicas or time they were started. See more details here https://github.com/VictoriaMetrics/VictoriaMetrics/pull/1257")
 	maxIdleConnections = flag.Int("datasource.maxIdleConnections", 100, `Defines the number of idle (keep-alive connections) to each configured datasource. Consider setting this value equal to the value: groups_total * group.concurrency. Too low a value may result in a high number of sockets in TIME_WAIT state.`)
-	roundDigits        = flag.Int("datasource.roundDigits", 0, `Adds "round_digits" GET param to datasource requests. `+
+	disableKeepAlive   = flag.Bool("datasource.disableKeepAlive", false, `Whether to disable long-lived connections to the datasource. `+
+		`If true, disables HTTP keep-alives and will only use the connection to the server for a single HTTP request.`)
+	roundDigits = flag.Int("datasource.roundDigits", 0, `Adds "round_digits" GET param to datasource requests. `+
 		`In VM "round_digits" limits the number of digits after the decimal point in response values.`)
 )
 
@@ -62,6 +64,7 @@ func Init(extraParams url.Values) (QuerierBuilder, error) {
 	if err != nil {
 		return nil, fmt.Errorf("failed to create transport: %w", err)
 	}
+	tr.DisableKeepAlives = *disableKeepAlive
 	tr.MaxIdleConnsPerHost = *maxIdleConnections
 	if tr.MaxIdleConns != 0 && tr.MaxIdleConns < tr.MaxIdleConnsPerHost {
 		tr.MaxIdleConns = tr.MaxIdleConnsPerHost
diff --git a/docs/vmalert.md b/docs/vmalert.md
index f01dcf6c55..c1ae5b979c 100644
--- a/docs/vmalert.md
+++ b/docs/vmalert.md
@@ -529,6 +529,8 @@ The shortlist of configuration flags is the following:
      Optional bearer auth token to use for -datasource.url.
   -datasource.bearerTokenFile string
      Optional path to bearer token file to use for -datasource.url.
+  -datasource.disableKeepAlive
+     Whether to disable long-lived connections to the datasource. If true, disables HTTP keep-alives and will only use the connection to the server for a single HTTP request.
   -datasource.lookback duration
      Lookback defines how far into the past to look when evaluating queries. For example, if the datasource.lookback=5m then param "time" with value now()-5m will be added to every query.
   -datasource.maxIdleConnections int