diff --git a/app/vmui/packages/vmui/src/components/Configurators/GlobalSettings/GlobalSettings.tsx b/app/vmui/packages/vmui/src/components/Configurators/GlobalSettings/GlobalSettings.tsx
index 420a048bee..4e3f60cbd3 100644
--- a/app/vmui/packages/vmui/src/components/Configurators/GlobalSettings/GlobalSettings.tsx
+++ b/app/vmui/packages/vmui/src/components/Configurators/GlobalSettings/GlobalSettings.tsx
@@ -16,6 +16,7 @@ import { useTimeDispatch, useTimeState } from "../../../state/time/TimeStateCont
 import ThemeControl from "../ThemeControl/ThemeControl";
 import useDeviceDetect from "../../../hooks/useDeviceDetect";
 import useBoolean from "../../../hooks/useBoolean";
+import { getTenantIdFromUrl } from "../../../utils/tenants";
 
 const title = "Settings";
 
@@ -57,6 +58,10 @@ const GlobalSettings: FC = () => {
   };
 
   const handlerApply = () => {
+    const tenantIdFromUrl = getTenantIdFromUrl(serverUrl);
+    if (tenantIdFromUrl !== "") {
+      dispatch({ type: "SET_TENANT_ID", payload: tenantIdFromUrl });
+    }
     dispatch({ type: "SET_SERVER", payload: serverUrl });
     timeDispatch({ type: "SET_TIMEZONE", payload: timezone });
     customPanelDispatch({ type: "SET_SERIES_LIMITS", payload: limits });
diff --git a/docs/CHANGELOG.md b/docs/CHANGELOG.md
index 86c991f9a1..aff0ba28f4 100644
--- a/docs/CHANGELOG.md
+++ b/docs/CHANGELOG.md
@@ -30,7 +30,7 @@ The following tip changes can be tested by building VictoriaMetrics components f
 * BUGFIX: [vmalert](https://docs.victoriametrics.com/vmalert.html): Properly set datasource query params. See [this issue](https://github.com/VictoriaMetrics/VictoriaMetrics/issues/4340). Thanks to @gsakun for [the pull request](https://github.com/VictoriaMetrics/VictoriaMetrics/pull/4341).
 * BUGFIX: [vmauth](https://docs.victoriametrics.com/vmauth.html): Properly handle LOCAL command for proxy protocol. See [this issue](https://github.com/VictoriaMetrics/VictoriaMetrics/issues/3335#issuecomment-1569864108).
 * BUGFIX: [vmbackupmanager](https://docs.victoriametrics.com/vmbackupmanager.html): Fixes crash on startup. See [this issue](https://github.com/VictoriaMetrics/VictoriaMetrics/issues/4378).
-
+* BUGFIX: [vmui](https://docs.victoriametrics.com/#vmui): fix bug with custom URL in global settings not respecting tenantID change. See [this issue](https://github.com/VictoriaMetrics/VictoriaMetrics/issues/4322).
 
 ## [v1.91.0](https://github.com/VictoriaMetrics/VictoriaMetrics/releases/tag/v1.91.0)