diff --git a/app/vmagent/remotewrite/pendingseries.go b/app/vmagent/remotewrite/pendingseries.go
index 92c6455ab..5b9f6548b 100644
--- a/app/vmagent/remotewrite/pendingseries.go
+++ b/app/vmagent/remotewrite/pendingseries.go
@@ -10,6 +10,7 @@ import (
 	"github.com/VictoriaMetrics/VictoriaMetrics/lib/decimal"
 	"github.com/VictoriaMetrics/VictoriaMetrics/lib/fasttime"
 	"github.com/VictoriaMetrics/VictoriaMetrics/lib/flagutil"
+	"github.com/VictoriaMetrics/VictoriaMetrics/lib/logger"
 	"github.com/VictoriaMetrics/VictoriaMetrics/lib/persistentqueue"
 	"github.com/VictoriaMetrics/VictoriaMetrics/lib/prompbmarshal"
 	"github.com/VictoriaMetrics/VictoriaMetrics/lib/promrelabel"
@@ -210,7 +211,22 @@ func pushWriteRequest(wr *prompbmarshal.WriteRequest, pushBlock func(block []byt
 		writeRequestBufPool.Put(bb)
 	}
 
-	// Too big block. Recursively split it into smaller parts.
+	// Too big block. Recursively split it into smaller parts if possible.
+	if len(wr.Timeseries) == 1 {
+		// A single time series left. Recursively split its samples into smaller parts if possible.
+		samples := wr.Timeseries[0].Samples
+		if len(samples) == 1 {
+			logger.Warnf("dropping a sample for metric with too long labels exceeding -remoteWrite.maxBlockSize=%d bytes", maxUnpackedBlockSize.N)
+			return
+		}
+		n := len(samples) / 2
+		wr.Timeseries[0].Samples = samples[:n]
+		pushWriteRequest(wr, pushBlock)
+		wr.Timeseries[0].Samples = samples[n:]
+		pushWriteRequest(wr, pushBlock)
+		wr.Timeseries[0].Samples = samples
+		return
+	}
 	timeseries := wr.Timeseries
 	n := len(timeseries) / 2
 	wr.Timeseries = timeseries[:n]
diff --git a/docs/CHANGELOG.md b/docs/CHANGELOG.md
index b49cf06a6..3c37fe5d1 100644
--- a/docs/CHANGELOG.md
+++ b/docs/CHANGELOG.md
@@ -26,6 +26,7 @@ The following tip changes can be tested by building VictoriaMetrics components f
 * BUGFIX: properly locate series with the given `name` and without the given `label` when using the `name{label=~"foo|"}` series selector. Previously such series could be skipped. See [this issue](https://github.com/VictoriaMetrics/VictoriaMetrics/issues/2255). Thanks to @jduncan0000 for discovering and fixing the issue.
 * BUGFIX: properly free up memory occupied by deleted cache entries for the following caches: `indexdb/dataBlocks`, `indexdb/indexBlocks`, `storage/indexBlocks`. This should reduce the increased memory usage starting from v1.73.0. See [this](https://github.com/VictoriaMetrics/VictoriaMetrics/issues/2242) and [this](https://github.com/VictoriaMetrics/VictoriaMetrics/issues/2007) issue.
 * BUGFIX: reduce the interval for checking for free disk space from 30 seconds to 1 second. This should reduce the probability of `no space left on device` panics when `-storage.minFreeDiskSpaceBytes` is set to too low values. See [this issue](https://github.com/VictoriaMetrics/VictoriaMetrics/issues/2305).
+* BUGFIX: [vmagent](https://docs.victoriametrics.com/vmagent.html): prevent from panic at vmagent when importing a time series with big number of samples. See [this issue](https://github.com/VictoriaMetrics/VictoriaMetrics/issues/2335). Thanks to @bleedfish for discovering and fixing the issue.
 
 
 ## [v1.74.0](https://github.com/VictoriaMetrics/VictoriaMetrics/releases/tag/v1.74.0)